D-Lysine

CAS Number 923-27-3
Molecular Formula C6H14N2O2
Molecular Weight 146.191 g/mol
InChI Key KDXKERNSBIXSRK-RXMQYKEDSA-N
LogP -2.28
Synonyms
  • D-Lysine
  • 923-27-3
  • EINECS 213-091-9
  • D-2,6-Diaminohexanoate
  • D-Lysin
  • DLY

Applications:


Separation of D-Lysine on Newcrom R1 HPLC column

D-Lysine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Separation of D-Lysine on Newcrom C18 HPLC column
Newcrom R1

This column is available in new type of hardware with only one connection end. Learn more about performance and advantage of this new hardware.



Application Analytes:

D-Lysine

HPLC Method for Analysis of L-Lysine and L-Arginine
l-Lysine , L-Arginine Chr_1106 L-Lysine is an essential amino acid required for growth and tissue repair, it can also help with anxiety. The amino acid is most often found in red meats,beans, fish, and dairy products. L-Arginine is an essential amino acid that is used to treat congestive heart failure, combat fatigue and circulatory diseases. It is also used to stimulate the immune system. Obelisc R is a reverse-phase column. It contains embedded ionic groups and can retain L-Lysine and L-Arginine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Condition

Column Obelisc R, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 10/90%
Buffer Na2HPO4 pH 6.0 - 25 mM
Flow Rate 1.0 ml/min
Detection UV, 210 nm
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds Arginine, L-Lysine


Application Analytes:

Arginine
D-Lysine
Lysine
N-Nitro-L-arginine

HPLC Determination of Lysine on Primesep 200 column in MS-compatible conditions
 

Condition

Column Primesep 200, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 10/90%
Buffer AmFM pH 3.0 - 10 mM
Flow Rate 1.0 ml/min
Detection CAD (Corona), MS- compatible phase
 

Description

Class of Compounds Acid, Hydrophilic, Ionizable, Carboxylic acid, Drug, Amino Acid
Analyzing Compounds Lysine
 

Application Analytes:

D-Lysine
Lysine