Darobactin

 

Molecular FormulaC47H55N11O12
Molecular Weight966.022
InChI KeyIAOIRKWNLBCFFO-KUDSBEMESA-N
Synonyms

    Applications:

    HPLC Determination of Darobactin on Primesep Columns

    December 23, 2019

    HPLC Determination of Darobactin on Primesep 200 Column_1212

    HPLC Determination of Darobactin on Primesep SB Column_1213
    The compound was discovered in Photorhabdus bacteria in 2019, living in the digestive systems of entomopathogenic nematodes. Researchers identified the nematode as a possible host because they feed on insects by targeting their larvae and releasing bacteria that then confront pathogens similar to those found in humans.

    In experiments, it cured mice of Escherichia coli and Klebsiella pneumoniae infections, without toxic side effects.

    Condition

    Column Primesep 200, Primesep SB
    Mobile Phase Gradient  MeCN
    Buffer Ammonium Formate pH 3.0
    Flow Rate 1.0 ml/min
    Detection UV 280 nm

    Description

    Class of Compounds Antibiotic
    Analyzing Compounds Darobactin

    Application Column

    Primesep 200

    The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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    Primesep SB

    The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

    Select options
    Application Analytes:
    Darobactin
    SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.