Delta-9-Tetrahydrocannabinol (THC)

CAS Number 1972-08-3
Molecular Formula C21H30O2
Molecular Weight 314.5 g/mol
InChI Key CYQFCXCEBYINGO-IAGOWNOFSA-N
LogP 7.0
Synonyms
  • Dronabinol
  • TETRAHYDROCANNABINOL
  • Marinol
  • delta9-Tetrahydrocannabinol
  • delta9-THC
  • Deltanyne
  • Dronabinolum
  • delta-9-tetrahydrocannabinol
  • Abbott 40566
  • delta-9-THC
  • 1972-08-3
  • delta(9)-THC
  • THC
  • delta1-THC
  • 1-trans-delta-9-Tetrahydrocannabinol
  • delta(sup 1)-Thc
  • delta(sup 9)-Thc
  • Namisol
  • Dronabinolum [Latin]
  • 9-tetrahydrocannabinol
  • delta(1)-Tetrahydrocannabinol
  • delta(9)-Tetrahydrocannabinol
  • (-)-delta9-trans-Tetrahydrocannabinol
  • delta1-Tetrahydrocannabinol
  • 1-trans-delta9-Tetrahydrocannabinol
  • delta(9)-Tetrahydrocannibinol
  • QCD 84924
  • SP 104
  • Syndros
  • delta(sup 1)-Tetrahydrocannabinol
  • delta(sup 9)-Tetrahydrocannabinol
  • L-delta1-trans-Tetrahydrocannabinol
  • QCD-84924
  • Cannabinol, delta1-tetrahydro-
  • CCRIS 4726
  • DEA No. 7369
  • CHEBI:66964
  • delta1-Tetrahydrocannabinol (VAN)
  • delta9-Tetrahydrocannabinol (VAN)
  • (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  • CHEMBL465
  • Tetrahydrocannabinols (-)-delta1-3,4-trans-form
  • (l)-delta(sup 1)-Tetrahydrocannabinol
  • 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol
  • 1-trans-delta(sup 9)-Tetrahydrocannabinol
  • UNII-7J8897W37S
  • HSDB 6471
  • Cannabinol, 1-trans-delta(sup 9)-tetrahydro-
  • CYQFCXCEBYINGO-IAGOWNOFSA-N
  • (-)-delta(sup 1)-3,4-trans-Tetrahydrocannabinol
  • 7J8897W37S
  • NSC 134454
  • Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol
  • 6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  • 6,6,9-Trimethyl-3-pentyl-7,8,9,10-tetrahydro-6H-dibenzo(b,d)pyran-1-ol
  • (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
  • 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-
  • trans-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol
  • .DELTA.9-Tetrahydrocannabinol
  • (-)-.DELTA.9-THC
  • delta(1)-THC
  • Compassia
  • Hashish
  • Relivar
  • Ganja
  • (L)-.delta.1-Tetrahydrocannabinol
  • Cannabis resin
  • Drona binol
  • (-)-.DELTA.1-Tetrahydrocannabinol
  • (-)-.DELTA.9-Tetrahydrocannabinol
  • Dronabinol [USAN:INN]
  • 9-ene-Tetrahydrocannabinol
  • L-.delta.1-trans-Tetrahydrocannabinol
  • L-trans-.delta.9-Tetrahydrocannabinol
  • delta-THC
  • (6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol
  • (6aR-trans)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol
  • 6H-Dibenzo
  • 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR,10aR)-
  • 6H-dibenzo[b,d]pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR,10aR)-
  • (-)-.DELTA.9-trans-Tetrahydrocannabinol
  • (-)-trans-.DELTA.9-Tetrahydrocannabinol
  • Marinol (TN)
  • THC-delta-9
  • .DELTA.1-THC
  • .DELTA.9-THC
  • Dronabinol (USP/INN)
  • trans-tetrahydrocannabinol
  • .DELTA.1-Tetrahydrocannabinol
  • Tetrahydrocannabinol delta9
  • (-)-trans-Delta9-THC
  • 9-delta-Tetrahydrocannabinol
  • Cannabinol, .DELTA.1-tetrahydro-
  • Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol
  • .DELTA.9-trans-Tetrahydrocannabinol
  • (l)-delta1-Tetrahydrocannabinol
  • 1-trans-D9-Tetrahydrocannabinol
  • L-.delta.1-Tetrahydrocannabinol
  • (-)-delta1-Tetrahydrocannabinol
  • (-)-delta9-Tetrahydrocannabinol
  • delta9-trans-Tetrahydrocannabinol
  • trans-delta9-Tetrahydrocannabinol
  • NSC-134454
  • (6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol
  • (6aR-trans)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol
  • 3-pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo[b,d]pyran-1-ol
  • CAT-310
  • 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-
  • trans-delta-9-Tetrahydrocannabinol
  • L-trans-delta9-Tetrahydrocannabinol
  • 6H-Dibenzo[b,d]pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-
  • DRG-0138
  • 14C-.DELTA.1-Tetrahydrocannabinol
  • L-delta(sup 1)-tetrahydrocannabinol
  • trans-.DELTA.9-Tetrahydrocannabinol
  • (-)-trans-Delta1-Tetrahydrocannabinol
  • (-)-trans-delta9-Tetrahydrocannabinol
  • .delta.-9-THC
  • 1-trans-delta(sup9)-tetrahydrocannabinol
  • (-)-delta9-(trans)-Tetrahydrocannabinol
  • .delta.(sup9)-THC
  • 3ls4
  • (-)-3,4-trans-Delta1-Tetrahydrocannabinol
  • 1-trans-.delta.(sup9)-tetrahydrocannabinol
  • DSSTox_CID_1327
  • (-)-.delta.(sup9)-trans-Tetrahydrocannabinol
  • Epitope ID:224552
  • SCHEMBL4609
  • delta 9-Tetrahydrocannabinol
  • delta-9 Tetrahydrocannabinol
  • DSSTox_RID_76083
  • DSSTox_GSID_21327
  • BIDD:GT0427
  • Dronabinol [USAN:USP:INN]
  • GTPL2424
  • Cannabinol, tetrahydro- (6CI)
  • DTXSID6021327
  • BDBM60994
  • CTK8D8346
  • US9416103, Delta9-THC
  • INT-0010
  • ZINC1530625
  • Tox21_112616
  • BDBM50007391
  • LS-975
  • NSC134454
  • PDSP2_000714
  • API0002497
  • Cannabinol, Delta1-tetrahydro- (7CI)
  • DB00470
  • INT-0010/06
  • (-)-Delta9-Tetrahydrocannabinol solution
  • 6465-30-1
  • CAS-1972-08-3
  • Synthetic THC in sesame oil / soft gelatin
  • C06972
  • Cannabinol, 1-trans-.delta.(sup9)-tetrahydro-
  • D00306
  • 23623-EP2269989A1
  • 23623-EP2275420A1
  • 23623-EP2298764A1
  • 23623-EP2298765A1
  • 23623-EP2298772A1
  • 23623-EP2308839A1
  • 23623-EP2314298A1
  • 23623-EP2314580A1
  • Dronabinol in sesame oil in soft gelatin capsule
  • 124699-EP2272825A2
  • 124699-EP2289509A2
  • 124699-EP2295426A1
  • 124699-EP2295427A1
  • 148820-EP2289509A2
  • Q190067
  • (-)-Delta9-THC (Dronabinol) 0.1 mg/ml in Methanol
  • (-)-Delta9-THC (Dronabinol) 1.0 mg/ml in Methanol
  • (-)-Delta9-THC (Dronabinol) 5.0 mg/ml in Methanol
  • Delta9-Tetrahydrocannabinol solution, ethanol solution
  • UNII-K4H93P747O component CYQFCXCEBYINGO-IAGOWNOFSA-N
  • 6H-Dibenzo[b, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-
  • Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-di benzo[b,d]pyran-1-ol
  • (-)-Delta9-Tetrahydrocannabinol (Delta9-THC) 100 microg/mL in Methanol
  • (-)-Delta9-Tetrahydrocannabinol (Delta9-THC) 1000 microg/mL in Methanol
  • 6,9-Trimethyl-3-pentyl-7,8,9,10-tetrahydro-6H-dibenzo[b,d]pyran-1-ol
  • 6H-Dibenzo[b, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-
  • (-)-(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  • (-)-delta(sup 1)-3,4-trans-Tetrahydrocannabinol(l)-delta(sup 1)-Tetrahydrocannabinol
  • (10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  • (6aR,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-dibenzo[b,d]pyran-1-ol
  • (6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6H,6AH,7H,8H,10AH-BENZO[C]ISOCHROMEN-1-OL
  • (6aS,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  • (S)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
  • 6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol(DeltaE-9-THC)
  • 6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-dibenzo[b,d]pyran-1-ol
  • 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-3-pentyl-6,6,9-trimethyl- (6ar-trans)-
  • 6H-Dibenzo[b, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-
  • 6H-Dibenzo[b,d]pyran-1-ol,6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-
  • Delta-9-Tetrahydrocannabinol, United States Pharmacopeia (USP) Reference Standard

Applications:


HPLC Separation of Ten Cannabinoids on Cannsep A Column

Condition

Column Cannsep A, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN 50-70% , 20 min
Buffer H2SO4 - 0.1%
Flow Rate 1.0 ml/min
Detection UV, 210 nm
 

Description

Class of Compounds Drug,  Hydrophilic, Ionizable, Supplements
Analyzing Compounds Cannabidivarin (CBDV), Tetrahydrocannabivarin (THCV), Cannabidiol (CBD) Delta-9-Tetrahydrocannabinol (THC), Cannabigerol (CBG), Cannabichromene (CBC), Tetrahydrocannabinolic acid (THCA-A)
 

Application Analytes:

Cannabidiol (CBD)
Cannabidiolic acid (CBDA)
Cannabidivarin (CBDV)
Cannabigerol (CBG)
Cannabinol (CBN)
Delta-8-Tetrahydrocannabinol (THC)
Delta-9-Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC)
Tetrahydrocannabinolic acid (THCA-A)
Tetrahydrocannabivarin (THCV)

HPLC Separation of Ten Cannabinoids on Cannsep B Column

Condition

Column Cannsep B, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN 50-70% , 25 min
Buffer H2SO4 - 0.1%
Flow Rate 1.0 ml/min
Detection UV, 210 nm
 

Description

Class of Compounds Drug,  Hydrophilic, Ionizable, Supplements
Analyzing Compounds Cannabidivarin (CBDV), Tetrahydrocannabivarin (THCV), Cannabidiol (CBD) Delta-9-Tetrahydrocannabinol (THC), Cannabigerol (CBG), Cannabichromene (CBC), Tetrahydrocannabinolic acid (THCA-A)
 

Application Analytes:

Cannabichromene (CBC)
Cannabidiol (CBD)
Cannabidiolic acid (CBDA)
Cannabidivarin (CBDV)
Cannabigerol (CBG)
Cannabinol (CBN)
Delta-9-Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC)
Tetrahydrocannabinolic acid (THCA-A)
Tetrahydrocannabivarin (THCV)

HPLC Separation of Ten Cannabinoids on Cannsep C Column

Condition

Column Cannsep C, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN 60-80% , 20 min
Buffer H2SO4 - 0.1%
Flow Rate 1.0 ml/min
Detection UV, 210 nm
 

Description

Class of Compounds Drug,  Hydrophilic, Ionizable, Supplements
Analyzing Compounds Cannabidivarin (CBDV), Tetrahydrocannabivarin (THCV), Cannabidiol (CBD) Delta-9-Tetrahydrocannabinol (THC), Cannabigerol (CBG), Cannabichromene (CBC), Tetrahydrocannabinolic acid (THCA-A)
 

Application Analytes:

Cannabichromene (CBC)
Cannabidiol (CBD)
Cannabidiolic acid (CBDA)
Cannabidivarin (CBDV)
Cannabigerol (CBG)
Cannabinol (CBN)
Delta-9-Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC)
Tetrahydrocannabinolic acid (THCA-A)
Tetrahydrocannabivarin (THCV)

HPLC Determination of THC in THC Infused Gummy Bear on Cannsep C Column

Condition

Column Cannsep C, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN 60-80%, 25 min, 5 min hold
Buffer H2SO4 - 0.1%
Flow Rate 1.0 ml/min
Detection UV, 210 nm
 

Description

Class of Compounds Drug,  Hydrophilic, Ionizable, Supplements
Analyzing Compounds Cannabidivarin (CBDV), Tetrahydrocannabivarin (THCV), Cannabidiol (CBD) Delta-9-Tetrahydrocannabinol (THC), Cannabigerol (CBG), Cannabichromene (CBC), Tetrahydrocannabinolic acid (THCA-A)
 

Application Analytes:

Cannabidiol (CBD)
Delta-9-Tetrahydrocannabinol (THC)
Tetrahydrocannabinol (THC)

HPLC Determination of CBD, CBN, Δ9-THC, Δ8-THC on Cannsep C Column
HPLC.cloud View on hplc.cloud Δ8-THC, Δ9-THC, CBD and CBN are cannabinoids found in Cannabis plants. They have some medical uses among which is the prevention of nausea and vomiting caused by some cancer medications. They can be separated using HPLC on a reverse-phase Cannsep C column using a mobile phase consisting of methanol (MeOH) and water with sulfuric acid (H2SO4) as buffer and UV detected at 200nm.

Condition

Column Cannsep C, 3.2x150 mm, 3 µm, 100A
Mobile Phase MeOH -80%,
Buffer H2SO4 - 0.2%
Flow Rate 1.0 ml/min
Detection UV, 200 nm
 

Description

Class of Compounds Drug,  Hydrophilic, Ionizable, Supplements
Analyzing Compounds  Cannabidiol (CBD) Delta-9-Tetrahydrocannabinol (THC), CBD, CBN, Δ9-THC, Δ8-THC
 

Application Analytes:

Cannabidiol (CBD)
Cannabinol (CBN)
Delta-8-Tetrahydrocannabinol (THC)
Delta-9-Tetrahydrocannabinol (THC)

HPLC Determination of Δ8-THC, CBD, Δ9-THC, CBN, on Primesep N Column
HPLC.cloud View on hplc.cloud Δ8-THC, Δ9-THC, CBD and CBN are cannabinoids found in Cannabis plants. They have some medical uses among which is the prevention of nausea and vomiting caused by some cancer medications. They can be separated using HPLC on a normal-phase Primesep N column using a mobile phase consisting of hexane and ethyl acetate without the need for a buffer with UV detection at 275nm.

Condition

Column Primesep N , 3.2x150 mm, 3 µm, 100A
Mobile Phase Hexane/Ethyl Acetate - 97/3%
Buffer No
Flow Rate 1.0 ml/min
Detection UV, 275 nm
 

Description

Class of Compounds Drug,  Hydrophilic, Ionizable, Supplements
Analyzing Compounds  Delta -8-Tetrahydrocannabinol, Δ8-THC, Cannabidiol (CBD), Delta-9-Tetrahydrocannabinol, Δ9-THC, Cannabinol (CBN)
 

Application Analytes:

Cannabidiol (CBD)
Cannabinol (CBN)
Delta-8-Tetrahydrocannabinol (THC)
Delta-9-Tetrahydrocannabinol (THC)