| CAS Number | 101-90-6 |
|---|---|
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.241 |
| InChI Key | WPYCRFCQABTEKC-UHFFFAOYSA-N |
| LogP | 1.16 |
| Synonyms |
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Applications:
HPLC Determination of Resorcinol Diglycidyl Ether on Newcrom R1
April 6, 2020
HPLC Method for Diglycidyl resorcinol ether on Newcrom R1 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Diglycidyl resorcinol ether.
Diglycidyl Resorcinol Ether, also called Resorcinol diglycidyl ether (RDGE), is a glycidyl ether with the C12H14O4. It is commercially available to reduce viscosity of epoxy resins. It is also highly toxic, potentially leading to irritation of skin, eyes, respiratory system, and skin. It is a known carcinogen with no safe levels of exposure.
Diglycidyl resorcinol ether can be retained and analyzed using the Newcrom R1 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) without a buffer. Detection is performed using UV.
| Column | Newcrom R1, 3.2 x 50 mm, 3 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O – 30/70% |
| Buffer | No |
| Flow Rate | 1.0 ml/min |
| Detection | UV 220 nm, MS-compatible mobile phase |
| Class of Compounds | Hydrophobic, Neutral |
| Analyzing Compounds | Diglycidyl resorcinol ether |
Application Column
Newcrom R1
Column Diameter: 3.2 mm
Column Length: 50 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended
Separation of Diglycidyl resorcinol ether on Newcrom R1 HPLC column
February 16, 2018
Diglycidyl resorcinol ether can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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