DMF (Dimethylformamide)

CAS Number 68-12-2
Molecular Formula HCON(CH3)2
Molecular Weight 73.09 g/mol
InChI Key ZMXDDKWLCZADIW-UHFFFAOYSA-N
LogP -1
Synonyms
  • N,N-DIMETHYLFORMAMIDE
  • Dimethylformamide
  • 68-12-2
  • N,N-Dimethylmethanamide
  • Dimethyl formamide
  • N-Formyldimethylamine
  • Formamide, N,N-dimethyl-
  • DMF
  • Dimethylformamid
  • Dimetilformamide
  • Dwumetyloformamid
  • DMFA
  • Formyldimethylamine
  • N,N-Dimethyl formamide
  • Dimethylforamide
  • Dimetylformamidu
  • DMF (amide)
  • NCI-C60913
  • n,n,dimethylformamide
  • N,N-Dimethylformamid
  • Dimethylamid kyseliny mravenci
  • Caswell No. 366A
  • Dimetylformamidu [Czech]
  • Dimethylformamid [German]
  • Dimetilformamide [Italian]
  • Dwumetyloformamid [Polish]
  • dimethyl-Formamide
  • HSDB 78
  • U-4224
  • UNII-8696NH0Y2X
  • CCRIS 1638
  • N,N-Dimetilformamida [Spanish]
  • n,n-dimethyl-Formamide
  • N, N-dimethylformamide

Applications:

HPLC Separation of Mixture of DMF and DMSO
Dimethylformamide, DMF, is primarily used as an organic solvent and is miscible with water and most other organic liquids. Dimethyl sulfoxide (DMSO) is also a solvent. It can dissolve both polar and nonpolar compounds and is miscible with water and other organic liquids. Both compounds can be retained and separated using anhydrous (water-free) conditions using HPLC by SHARC 1 column, which uses hydrogen-bonding as a separation mechanism. The method uses a gradient of acetonitrile (ACN) and methanol (MeOH) mobile phase without the need for a buffer. UV detection used at 220nm.

Condition
Column Sharc 1, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 98-85 %, 10 min
Buffer No
Flow Rate 1.0 ml/min
Detection UV, 220 nm
 

Description
Class of Compounds Drug, Basic, Hydrophobic, Ionizable, Zwitterionic
Analyzing Compounds DMF, DMSO
 
Application Analytes:

DMF (Dimethylformamide)
DMSO (Dimethyl sulfoxide)
HPLC Method For Analysis Of Dimethylformamide and Dimethylacetamide on Primesep 100 Column
Separation type: Liquid Chromatography Mixed-mode

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High Performance Liquid Chromatography (HPLC) Method for Analysis of Dimethylformamide and Dimethylacetamide

Condition
Column Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 5/95%
Buffer H3PO4 - 0.2%
Flow Rate 1.0 ml/min
Detection UV, 200 nm,
 

Description
Class of Compounds Amide
Analyzing Compounds TDimethylformamide,  Dimethylacetamide
 
Application Analytes:

DMA (Dimethylacetamide)
DMF (Dimethylformamide)