Fenofibrate

CAS Number 49562-28-9
Molecular Formula C20H21ClO4
Molecular Weight 360.830 g/mol
InChI Key YMTINGFKWWXKFG-UHFFFAOYSA-N
LogP 4.71
Synonyms
  • Fenofibrate
  • Propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
  • Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester
  • 49562-28-9
  • Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester
  • 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methylethyl ester
  • Ankebin
  • Clorofibrate
  • Elasterin
  • Fenobrate
  • Fenofibrat
  • fenofibrato
  • Fenogal
  • Fenotard
  • Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate
  • Lipanthyl
  • Lipantil
  • Lipicard
  • Lipidil
  • Lipidil Supra
  • Lipirex
  • Lipoclar
  • Lipofene
  • Liposit
  • MeltDose
  • Nolipax
  • NSC 281319
  • Procetofen
  • Procetofene
  • Procetoken
  • Protolipan
  • Secalip
  • BRN 2062462
  • 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
  • EINECS 256-376-3
  • Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
  • Lipidex
  • Lipifen
  • Proctofene
  • Sedufen
  • Elasterate
  • Luxacor
  • Triglide
  • Lipofen
  • Fenoglide
  • Fenofibratum
  • UNII-U202363UOS
  • FNF
  • Finofibrate
  • Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
  • Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
  • Lipantil (TN)
  • Tricor (TN)

Applications:


HPLC Method for Analysis of Fenofibrate
8 Fenofibrate is a synthetic Peroxisome Proliferator Receptor alpha (PPAR alpha) Agonist as well as an antilipemic agent. It is used to help lower "bad" cholesterol and fats (LDL, triglycerides) by increasing the natural enzyme that breaks down fats in the blood. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Propranolol. The method is UV compatible and can be used as a general approach for analyzing similar compounds.  

Condition

Column Primesep 200, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeCN - 50%
Buffer H3PO4 - 0.1%,
Flow Rate 0.5 ml/min
Detection UV, 270 nm
 

Application Analytes:

Fenofibrate

Description

Class of Compounds Drug,  Acid, Hydrophilic, Ionizable, Supplements
Analyzing Compounds Fenofibrate