Fentanyl

CAS Number 437-38-7
Molecular Formula C22H28N2O
Molecular Weight 336.480 g/mol
InChI Key PJMPHNIQZUBGLI-UHFFFAOYSA-N
LogP 4.05
Synonyms
  • Fentanyl
  • N-Phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
  • Propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-
  • 437-38-7
  • 5-22-08-00049
  • Propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-
  • 1-Phenethyl-4-(N-phenylpropionamido)piperidine
  • 1-Phenethyl-4-N-propionylanilinopiperidine
  • Durogesic
  • Fentanest
  • Fentanil
  • fentanila
  • Fentora
  • N-[1-(2-Phenylethyl)-4-piperidinyl]propionanilide
  • Phentanyl
  • Propionanilide, N-(1-phenethyl-4-piperidyl)-
  • Sublimase
  • BRN 0494484
  • EINECS 207-113-6
  • Fentanylum
  • N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
  • N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
  • Sentonil
  • Duragesic-100
  • Duragesic-12
  • Duragesic-25
  • Duragesic-50
  • Duragesic-75
  • Fentanyl-100
  • Fentanyl-12
  • Fentanyl-25
  • Fentanyl-50
  • Fentanyl-75
  • UNII-UF599785JZ
  • Matrifen
  • Fentanyl Transdermal System
  • Fentanyl buccal
  • Durotep MT
  • Lazanda
  • N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
  • N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide
  • N-(1-phenethyl-4-piperidyl)propionanilide
  • N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
  • N-phenethyl-4-(N-propionylanilino)piperidine
  • N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide

Applications:


Separation of Fentanyl on Newcrom R1 HPLC column

Fentanyl can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Separation of Fentanyl on Newcrom R1 HPLC column
Newcrom R1

This column is available in new type of hardware with only one connection end. Learn more about performance and advantage of this new hardware.



Application Analytes:

Fentanyl

HPLC Determination of Fentanyl on Primesep 200 Column
HPLC Determination of Fentanyl  

Condition

Column Primesep 200, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 60/40%
Buffer H3PO4 - 0.1 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm
 

Description

Class of compounds Narcotic, Drug, Basic, Hydrophobic, Ionizable, Zwitterionic
Analyzing Compounds Fentanyl
 

Application Analytes:

Fentanyl
Fentanyl citrate