| CAS Number | 98-00-0 |
|---|---|
| Molecular Formula | C5H6O2 |
| Molecular Weight | 98.101 |
| InChI Key | XPFVYQJUAUNWIW-UHFFFAOYSA-N |
| LogP | 0.28 |
| Synonyms |
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Applications:
HPLC Method for Substituted Furans Separation on Newcrom R1 column
February 10, 2021
HPLC Method for 5-Hydroxymethyl-2-furaldehyde (5-HMF), Furfuryl alcohol, Furfural, 2-Furancarboxylic acid, 3,4-Bis(hydroxymethyl)furan, 5-Hydroxymethyl-2-furancarboxylic acid on Newcrom R1 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of 5-Hydroxymethyl-2-furaldehyde (5-HMF), Furfuryl alcohol, Furfural, 2-Furancarboxylic acid, 3,4-Bis(hydroxymethyl)furan, 5-Hydroxymethyl-2-furancarboxylic acid.
Furan is a chemical contaminant that forms in some foods during traditional heat treatment techniques, such as cooking, jarring, and canning.
5-Hydroxymethyl-2-furaldehyde (5-HMF), also known as Hydroxymethylfurfural, is an organic compound with the chemical formula C6H6O3. It can form in sugar-containing food when heated. Due to being considered a potential carcinogen, much research has gone into it’s formation.
Furfuryl alcohol is a trapping agent with the chemical formula C5H6O2. It is used to synthesize ethyl levulinate, prepare collodial microporous carbon spheres, and as a starting material to prepare cyclopentanone.
Furfural is an organic compound with the chemical formula C5H4O2. IT is found primarily in cooked or heated coffee and whole grain bread. It is used as a renewable chemical feedstock, which can be converted into a variety of useful chemicals.
2-Furancarboxylic acid is an organic compound with the chemical formula C5H4O3. It is used primarily in the production of furoate esters, some of which are drugs and pesticides. As a flavoring, it is used for it’s sweet, oily, and earthly flavor.
5-Hydroxymethyl-2-furaldehyde (5-HMF), Furfuryl alcohol, Furfural, 2-Furancarboxylic acid, 3,4-Bis(hydroxymethyl)furan, 5-Hydroxymethyl-2-furancarboxylic acid can be retained and separated in HPLC using Newcrom R1 reverse-phase column. The analytical method’s mobile phase consists of a gradient of acetonitrile (ACN) in water with phosphoric acid (H3PO4) buffer and using UV detection at 210 and 275 nm.
| Column | Newcrom R1, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O – 5/95% |
| Buffer | H3PO4 – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | 210, 275 nm |
| Class of Compounds | Hydrophilic, Acid, Aldehyde |
| Analyzing Compounds | 5-Hydroxymethyl-2-furaldehyde (5-HMF), Furfuryl alcohol, Furfural, 2-Furancarboxylic acid, 3,4-Bis(hydroxymethyl)furan, 5-Hydroxymethyl-2-furancarboxylic acid |
Application Column
Newcrom R1
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
3,4-Bis(hydroxymethyl)furan
5-Hydroxymethyl-2-furaldehyde (5-HMF)
5-Hydroxymethyl-2-furancarboxylic acid
Furfural
Furfuryl alcohol
Separation of Furfuryl alcohol on Newcrom R1 HPLC column
February 16, 2018
Furfuryl alcohol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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