HPLC Determination of Ritodrine on Primesep 100

HPLC Determination of Ritodrine_1181
Ritodrine (also Yutopar), is a drug used in relaxation of smooth muscle and to stop premature labor. It has been pulled from the US market due to its side effects. Ritodrine can be retained on a Primesep 100 column with great peak shape using isocratic method of 30/70 Acetonitrile (ACN) and water with 0.3% sulfuric acid as buffer. UV Detection 276nm.
 

Condition

Column Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 30/70%
Buffer H2SO4 - 0.3 %
Flow Rate 1.0 ml/min
Detection UV, 276 nm
 

Description

Class of Compounds Drug, Basic, Hydrophobic, Ionizable, Amine
Analyzing Compounds Ritodrine
 

Application Analytes:

Ritodrine