HPLC Method for Ritodrine on Primesep 100 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Ritodrine
Ritodrine (also Yutopar), is a drug used in relaxation of smooth muscle and to stop premature labor. It has been pulled from the US market due to its side effects. Ritodrine can be retained on a Primesep 100 column with great peak shape using isocratic method of 30/70 Acetonitrile (ACN) and water with 0.3% sulfuric acid as buffer. UV Detection 276nm.
Condition
Column Primesep 100, 4.6×150 mm, 5 µm, 100A Mobile Phase MeCN/H2O – 30/70% Buffer H2SO4 – 0.3 % Flow Rate 1.0 ml/min Detection UV, 276 nm
Description
Class of Compounds
Drug, Basic, Hydrophobic, Ionizable, Amine Analyzing Compounds Ritodrine
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended