HPLC Separation of Mixture of 2-Hydroxyethyl Salicylate and Salicylic Acid on Primesep B Column

HPLC Separation of Mixture of 2-Hydroxyethyl Salicylate and Salicylic Acid_1182 2-Hydroxyethyl salicylate is a drug used as analgesic agents for the treatment of mild to moderate pain.  

Condition

Column Primesep B, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 25/75%
Buffer H2SO4 - 0.5 %
Flow Rate 1.0 ml/min
Detection UV, 238 nm
 

Description

Class of Compounds Acid, Hydrophilic, Ionizable, Carboxylic acid, Drug, Carbocyclic, Benzoate, Hydroxy Acid, Hydroxybenzoate, Phenol
Analyzing Compounds 2-Hydroxyethyl Salicylate, Salicylic Acid
 

Application Analytes:

2-Hydroxyethyl salicylate
Salicylic acid