Hydroxypropyl B-Cyclodextrin

CAS Number94035-02-6
Molecular FormulaC54H102O39
Molecular Weight1375.4
InChI KeyBZRWCHBEBFPRGF-UHFFFAOYSA-N
Synonyms
  • 94035-02-6
  • Hydroxypropyl-|A-Cyclodextrin
  • 2-Hydroxypropy-.beta.-cyclodextrin
  • BCP28369
  • AKOS015901120
  • AS-60727
  • FT-0700836
  • A19428
  • 2-Hydroxypropy-.beta.-cyclodextrin;2-Hydroxypropylether-b-cyclodextrin

Applications:

Uv-Vis Spectrum of Hydroxypropyl-b-Cyclodextrin

March 30, 2026

Access the UV-Vis Spectrum SIELC Library

If you are looking for optimized HPLC method to analyze Hydroxypropyl B-Cyclodextrin check our HPLC Applications library

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. This analysis was done with the mobile phase made of 20% acetonitrile and 80% water.

Application Analytes:
Hydroxypropyl B-Cyclodextrin
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method For Analysis of B-Cyclodextrin and Hydroxypropyl B-Cyclodextrin on Primesep S2 Column

September 28, 2021

HPLC Method for beta-CYCLODEXTRIN, Hydroxypropyl B-Cyclodextrin on Primesep S2 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of B-Cyclodextrin and Hydroxypropyl B-Cyclodextrin.

Beta-cyclodextrin has the chemical formula C42H70O35. It is used in a large variety of industries primarily as a complexing agent.  It’s most notable uses are in medicine as sustained release drugs carrier and to improve stability in drugs.

Hydroxypropyl B-Cyclodextrin is a Oligosaccharide drug with the chemical formula C63H112O42. It is used as a complexing agent.

Condition
Column Primesep S2, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN- 70%
Buffer No
Flow Rate 1.0 ml/min
Detection ELSD

Description
Class of Compounds Sugar
Analyzing Compounds beta-CYCLODEXTRIN, Hydroxypropyl B-Cyclodextrin

 

Application Column

Primesep S2

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Hydroxypropyl B-Cyclodextrin
beta-CYCLODEXTRIN
Application Detection:
ELSD Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.