Imidazolidinyl urea

Imidazolidinyl urea structural formula

CAS Number39236-46-9
Molecular FormulaC11H16N8O8
Molecular Weight388.297
InChI KeyZCTXEAQXZGPWFG-UHFFFAOYSA-N
LogP-4.01
Synonyms
  • Imidazolidinyl urea
  • N,N'-Methylenebis{N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea}
  • Urea, N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-
  • 39236-46-9
  • Urea, N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-
  • Euxyl K 200
  • Germal II
  • Germall 115
  • Imidurea
  • N,N''-Methylenbis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]harnstoff]
  • N,N''-Methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]]urea
  • N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea]
  • N,N''-Methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]uree]
  • N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidine-4-yl]uree]
  • N,N''-metilenbis[N'-[3-(hidroximetil)-2,5-dioxoimidazolidin-4-il]urea]
  • Sepicide CI
  • UREA, N,N-METHYLENEBIS[N'-[3-(HYDROXYMETHYL)-2,5-DIOXOIMIDAZOLIDIN-4-YL]
  • Urea, N,N'-methylenebis[N'-[3-hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-
  • EINECS 254-372-6
  • UNII-M629807ATL
  • N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea)
  • methanebis(N,N'-(5-ureido-2,4-diketotetrahydroimidazole)-N,N-dimethylol)
  • 82852-50-4

Applications:

HPLC Determination of Imidazolidinyl urea on SHARC 1 Column

February 1, 2021

Separation type: Liquid Chromatography HILIC




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High Performance Liquid Chromatography (HPLC) Method of Imidazolidinyl urea.


Imidazolidinyl urea is used in cosmetics as a preservative due to its antimicrobial properties. It is active against a broad spectrum of gram positive and gram negative bacteria, yeast and molds. It can be retained in HPLC using a SHARC 1 column, which uses hydrogen-bonding as a separation mechanism. The isocratic method uses a mobile phase of acetonitrile (ACN) and water. Imidazolidinyl urea can be monitored by low UV (210 nm), ELSD, CAD or LC/MS.



Condition
Column Sharc 1, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/MeOH – 90/10%
Buffer No
Flow Rate 1.0 ml/min
Detection UV 210 nm

 

Description
Class of Compounds
 Hydrophilic, Amide, Amine
Analyzing Compounds Imidazolidinyl urea

 

Application Column

SHARC 1

The SHARC™ family of innovative columns represents the first commercially available columns primarily utilizing separation based on hydrogen bonding. SHARC stands for Specific Hydrogen-bond Adsorption Resolution Column. Hydrogen bonding involves an interaction or attraction between a bound hydrogen atom and molecules containing electronegative atoms, such as oxygen, nitrogen, and fluorine.

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Application Analytes:
Imidazolidinyl urea
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Imidazolidinyl urea on Newcrom R1 HPLC column

February 16, 2018
Separation of Imidazolidinyl urea on Newcrom C18 HPLC column

Imidazolidinyl urea can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Imidazolidinyl urea
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.