Iodide

CAS Number 20461-54-5
Molecular Formula I-
Molecular Weight 126.9045 g/mol
InChI Key XMBWDFGMSWQBCA-UHFFFAOYSA-M
LogP 2.9
Synonyms
  • Iodide
  • Iodide ion
  • trihydridoiodine
  • 20461-54-5
  • Iodide(1-)
  • Iodide-127
  • iodinane
  • iodine anion
  • Iodide anion
  • Iodide Salt
  • lambda(3)-iodane
  • UNII-09G4I6V86Q
  • I-
  • 09G4I6V86Q
  • Colloidal iodine
  • Iodine ion
  • Iodide ion(1-)
  • Iodine(1-)
  • Iodine, ion (I1-)
  • hydriodic acid, ion(1-)
  • CHEMBL185537
  • BDBM26981
  • CHEBI:16382
  • CHEBI:37181
  • CTK1A4386
  • DTXSID80912339
  • [IH5]
  • Iodide (6CI,7CI,8CI,9CI)
  • Ba 2796
  • DB12754
  • C00708
  • Q407654
  • Q27117062

Applications:


HPLC Method for Analysis of Iodide and Thyroid Hormones
  Iodine is an important element in production of thyroid hormones, T3 and T4, which are essential regulators of organism's metabolism. The glands' concentration of Iodide, hormones T3 and T4, along with their precursors: 3,5-Diiodo-L-thyronine (T2), 3,5-Diiodo-L-tyrosine (DIT), and 3-Iodo-L-tyrosine (MIT) can now be studied simultaneously with this HPLC method.  In order to analyze the hydrophobic hormones along with iodide (a very polar inorganic ion) a special mixed-mode column, Primesep D, was used.  This column provides both strong hydrophobic and anion exchange properties.  The Primesep D silica-bonded ligand is comprised of a long alkyl chain and an embedded amino functional group.  The TFA was used as an ionic modifier to provide stable acidic pH and sufficient ion strength for the mobile phase.  The mobile phase composition is suitable for UV, MS, ELSD, and CAD detection.  

Condition

Column Primesep D, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN
Buffer TFA
Flow Rate 1.0 ml/min
Detection UV, 230 nm
 

Description

Class of Compounds Drug,  Hydrophilic, Ionizable, Supplements
Analyzing Compounds T3, T4, 3,5-Diiodo-L-thyronine (T2), 3,5-Diiodo-L-tyrosine (DIT), and 3-Iodo-L-tyrosine (MIT)
 

Application Analytes:

3,5-Diiodo-L-thyronine (T2)
3,5-Diiodo-L-tyrosine dihydrate (DIT)
3-Iodo-L-tyrosine (MIT)
Iodide
Iodine
Levothyroxine (T4)
Liothyronine (T3)
Methimazole

HPLC Separation of Inorganic Anions on Newcrom BH Column
HPLC.cloud View on hplc.cloud      

Condition

Column Newcrom BH, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 10/90%
Buffer Gradient AmAc pH 5.0 -  20-90 mM , 20 min
Flow Rate 1.0 ml/min
Detection CAD (Corona)  (MS-compatible mobile phase)

Description

Class of Compounds Ions, Hydrophilic, Ionizable
Analyzing Compounds Sodium, Phosphate, Chloride, Bromide, Nitrate, Iodide, Sulfate,  Perchlorate


Application Analytes:

Bromide
Chloride
Iodide
Iodine
Nitrate
Perchlorate
Phosphate
Sodium
Sulfate

HPLC Determination of Iodide on Primesep SB
HPLC.cloud View on hplc.cloud  

Condition

Column Primesep SB, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 50/50%
Buffer HClO4 - 0.5%
Flow Rate 0.5 ml/min
Detection UV 228 nm
 

Description

Class of Compounds Ion
Analyzing Compounds Iodide
 

Application Analytes:

Iodide