Lipitor

Lipitor

CAS Number134523-03-8
Molecular FormulaC66H68CaF2N4O10
Molecular Weight1155.363
InChI KeyFQCKMBLVYCEXJB-MNSAWQCASA-L
Synonyms
  • Atorvastatin calcium
  • Calcium bis{(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate}
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, (betaR,deltaR)- (2:1)
  • 134523-03-8
  • Lipitor
  • Lorvast
  • PD 134298-38A
  • UNII-C0GEJ5QCSO
  • Storvas
  • Rotacor
  • Ranbaxy's Storvas
  • Atorvastatin calcium anhydrous
  • Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2)
  • 334757-04-9
  • 1108202-55-6
  • 1370463-14-1

Applications:

HPLC Method for Analysis of Atorvastatin

May 31, 2018

 

Condition

Column Newcrom R1 3.2×100 mm, 3 µm, 100A
Mobile Phase MeCN/H2O – 50/50%
Buffer H3PO4 – 0.1 %
Flow Rate 0.5 ml/min
Detection UV, 270 nm

 

Description

Class of Compounds
Drug, Statin, Hydrophobic, Ionizable
Analyzing Compounds Atorvastatin

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Atorvastatin
Lipitor
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Lipitor

May 6, 2016

Chr_1069

 

Condition

Column Primesep 200, 3.2×100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 30-65%, 5 min, 4 min hold
Buffer Gradient H3PO4 0.05 – 0.3% , 5 min, 4 min hold
Flow Rate 1.0 ml/min
Detection UV, 270 nm

 

Description

Class of Compounds
Drug, Statin, Hydrophobic, Ionizable
Analyzing Compounds Atorvastatin, Lipitor

 

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Atorvastatin
Lipitor

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.