Meclizine

CAS Number 569-65-3
Molecular Formula C25H27ClN2
Molecular Weight 390.960 g/mol
InChI Key OCJYIGYOJCODJL-UHFFFAOYSA-N
LogP 4.64
Synonyms
  • Meclizine
  • 1-[(4-Chlorophenyl)(phenyl)methyl]-4-[(3-methylphenyl)methyl]piperazine
  • Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-
  • 569-65-3
  • Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-
  • (.+-.)-Meclizine
  • 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine
  • 1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)piperazine
  • 1-(p-Chlorobenzohydryl)-4-(m-methylbenzyl) piperazine
  • 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl) piperazine
  • 1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)piperazine
  • Ancolan
  • Histametizyne
  • Meclozin
  • meclozina
  • Meclozine
  • Navicalm
  • Neo-Istafene
  • NSC 169189
  • Parachloramine
  • Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-
  • Postafene
  • Ravelon
  • Suprimal
  • U.C.B. 5062
  • Vomisseis
  • Bonadettes
  • BRN 0332002
  • Calmonal
  • Chiclida
  • 1-p-Chlorobenzhydryl-4-m-methylbenzylpiperazine
  • 1-(p-Chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)piperazine
  • 1-((4-Chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)piperazine
  • EINECS 209-323-3
  • Histamethine
  • Histamethizine
  • Histametizine
  • Itinerol
  • Monamine
  • Neo-suprimal
  • Neo-suprimel
  • Peremesin
  • Sea-Legs
  • Siguran
  • Travelon
  • (+-)-Meclizine
  • Dramamine II
  • Meclozinum
  • UNII-3L5TQ84570

Applications:


HPLC Method for Analysis of Meclizine


Meclizine is a histamine H1 antagonist and a synthetic piperazine. It is used to prevent and treat motion sickness, vertigo, and nausea during pregnancy. The side effects that may occur include drowsiness, dry mouth, and tiredness. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Analytes:

Meclizine