| CAS Number | 74-88-4 |
|---|---|
| Molecular Formula | CH3I |
| Molecular Weight | 141.939 |
| InChI Key | INQOMBQAUSQDDS-UHFFFAOYSA-N |
| LogP | 1.51 |
| Synonyms |
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Applications:
Uv-Vis Spectrum of Iodomethane
February 20, 2026
Access the UV-Vis Spectrum SIELC Library
If you are looking for optimized HPLC method to analyze Iodomethane (Methyl iodide) check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
HPLC Method For Analysis Of Iodomethane (Methyl iodide)
December 28, 2021
HPLC Method for Iodomethane (Methyl iodide) on Newcrom R1 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Iodomethane (Methyl iodide)
Iodomethane, also known as Methyl iodide, is a compound with the chemical formula CH3I. It is a volatile liquid that is produced by rice, algae, fungi, and kelp. It is used as a pesticide, more specificly as a pre-plant biocide for a variety of plants. California Department of Pesticide Regulation (DPR) declared that iodomethane is toxic, leading it to no longer being used in Californian soil.
Iodomethane (Methyl iodide) can be retained and analyzed using the Newcrom R1 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN). Detection is performed using UV.
| Column | Newcrom R1, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O – 50/50% |
| Buffer | No |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 250 nm |
| Class of Compounds |
Haloalkane |
| Analyzing Compounds | Iodomethane (Methyl iodide) |
Application Column
Newcrom R1
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Separation of Methyl iodide on Newcrom R1 HPLC column
February 16, 2018
Methyl iodide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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