Metoprolol

Metoprolol structural formula

UV Spectra of Metoprolol

UV Metoprolol spectra

 

 

 

CAS Number51384-51-1
Molecular FormulaC15H25NO3
Molecular Weight267.369
InChI KeyIUBSYMUCCVWXPE-UHFFFAOYSA-N
LogP1.88
Synonyms
  • Metoprolol
  • 1-[4-(2-Methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol
  • 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-
  • 51384-51-1
  • 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-
  • (.+-.)-Metoprolol
  • (RS)-Metoprolol
  • 1-(isopropilamino)-3-[4-(2-metoxietil)fenoxi]propan-2-ol
  • 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
  • 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propane-2-ol
  • 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol
  • 1-Isopropylamino-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
  • Beatrolol
  • dl-Metoprolol
  • Meijoprolol
  • Metocard
  • Metohexal
  • Seroken
  • Spesicor
  • EINECS 257-166-4
  • UNII-GEB06NHM23
  • Neobloc
  • Loresor
  • (+/-)-Metoprolol
  • Lopresor
  • Lopresoretic
  • Lopressor
  • Metoprolol succinate
  • Metoprolol tartrate
  • Metoprololum
  • Preblok
  • Presolol
  • Seloken
  • Toprol-XL
  • {2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}(propan-2-yl)amine
  • 37350-58-6
  • 54163-88-1

Applications:

HPLC Method for Analysis of Metoprolol in Tablets on Primesep 200 Column

June 29, 2018


HPLC Method for Analysis of MetoprololMetoprolol is a beta-blocker that is used to treat high blood pressure, angina, and heart failure by blocking beta-1 adrenergic receptors. At it’s most effective, it can lower the risk of death after a heart attack.

Condition
Column Primesep 200, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 50/50%
Buffer H3PO4 – 0.5 %
Flow Rate 1.0 ml/min
Detection UV, 223 nm

Description
Class of Compounds
 Drug, Beta-blocker, Hydrophobic, Basic
Analyzing Compounds Metoprolol

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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Application Analytes:
Metoprolol
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.