Minocycline hydrochloride

CAS Number 13614-98-7
Molecular Formula C23H28ClN3O7
Molecular Weight 493.941 g/mol
InChI Key GLMUAFMGXXHGLU-VQAITOIOSA-N
LogP -0.139
Synonyms
  • Minocycline hydrochloride
  • (4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide--hydrogen chloride (1/1)
  • 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-, hydrochloride (1:1)
  • 13614-98-7
  • EINECS 237-099-7
  • Minocin
  • Minocycline chloride
  • Minomax
  • Minomycin
  • Mynocine hydrochloride
  • Tri-mino
  • Arestin
  • Solodyn
  • Minocycline HCl
  • Periocline
  • UNII-0020414E5U
  • Klinomycin

Applications:


HPLC Method For Analysis Of Minocycline hydrochloride on Newcrom R1 Column
Minocycline hydrochloride is a tetracycline antibiotic used to treat a wide variety of bacterial infections as well as treatment of acne vulgaris

Condition

Column Newcrom R1, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 5/95%
Buffer TEAPh - 20 mM, pH 2.0
Flow Rate 0.5 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds Drug, Antibiotics
Analyzing Compounds Minocycline hydrochloride
 

Application Analytes:

Minocycline hydrochloride

HPLC Method For Analysis Of Minocycline on Primesep 100 column
Separation type: Liquid Chromatography Mixed-mode

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High Performance Liquid Chromatography (HPLC) Method for Analysis of Minocycline hydrochloride

Minocycline is in a class of medications called tetracycline antibiotics. It works in treatment of infections by preventing the growth and spread of bacteria. Minocycline can be retained on the Primesep 100 mixed-mode column using an isocratic analytical method with a simple mobile phase of water, acetonitrile (MeCN, ACN), and sulphuric acid (H2SO4) buffer. The analysis method can be UV detected at 270 nm.

Condition

Column Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 50/50%
Buffer H2SO4 - 0.5%
Flow Rate 1.0 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds Drug, Antibiotics
Analyzing Compounds Minocycline hydrochloride
 

Application Analytes:

Minocycline hydrochloride