Montelukast

CAS Number 158966-92-8
Molecular Formula C35H36ClNO3S
Molecular Weight 586.191 g/mol
InChI Key UCHDWCPVSPXUMX-TZIWLTJVSA-N
LogP 7.72
Synonyms
  • Montelukast
  • {1-[({(1R)-1-{3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid
  • Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-
  • 158966-92-8
  • Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-
  • (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
  • 1-((((1R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
  • UNII-MHM278SD3E
  • Aerokast

Applications:


HPLC Method for Analysis of Montelukast
Chr_1049

Montelukast is a leukotriene receptor antagonist (LTRA) used to relieve symptoms of allergies (crying, sneezing, itching, etc.) and treatment of asthma (specifically to prevent the wheezing and shortness of breath). Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Montelukast. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Analytes:

Montelukast