Mycophenolate mofetil

CAS Number 128794-94-5
Molecular Formula C23H31NO7
Molecular Weight 433.501 g/mol
InChI Key RTGDFNSFWBGLEC-SYZQJQIISA-N
LogP 3.2
Synonyms
  • mycophenolate mofetil
  • 128794-94-5
  • CellCept
  • RS 61443
  • 115007-34-6
  • RS-61443
  • TM-MMF
  • Munoloc
  • Mycophenolic acid morpholinoethyl ester
  • Mycophenylate mofetil
  • Mycophenolatemofetil
  • UNII-9242ECW6R0
  • HSDB 7436
  • Cellcept (TN)
  • 2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
  • CHEBI:8764
  • C23H31NO7
  • Mycophenolate mofetil (CellCept)
  • 9242ECW6R0
  • 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
  • Myfenax
  • RS-61443-190
  • DSSTox_CID_3340
  • DSSTox_RID_76982
  • Mycophenolate mofetil, 98%
  • DSSTox_GSID_23340

Applications:


HPLC Determination of Mycophenolate Mofetil on Primesep SB Column
HPLC Determination of Mycophenolate mofetil Mycophenolate mofetil alongside other medicines is used as an immunosuppressant to prevent organ rejection after a transplant. THe compound can be retained in HPLC using Primesep SB mixed-mode column that has both hydrophobic and anion-exchange properties. The analytical method’s mobile phase consists of a gradient of acetonitrile (ACN) in water with phosphoric acid (H3PO4) buffer and using UV detection at 250nm.

Condition

Column Primesep SB, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-20%, 10 min
Buffer H3PO4 - 0.2 %
Flow Rate 1.0 ml/min
Detection UV, 250 nm
 

Description

Class of Compounds Drug, Hydrophobic, Ionizable, Carbocyclic, Benzoate
Analyzing Compounds Mycophenolate Mofetil
 

Application Analytes:

Mycophenolate mofetil

HPLC Separation of Mixture of Mycophenolate mofetil and Mycophenolic Acid on Newcrom R1 Column
Mycophenolate mofetil and mycophenolic acid alongside other medicines are used as immunosuppressants to prevent organ rejection after a transplant. Both compounds can be retained and separated in HPLC using Newcrom R1 reverse-phase column. The analytical method’s mobile phase consists of a gradient of acetonitrile (ACN) in water with phosphoric acid (H3PO4) buffer and using UV detection at 220nm.

Condition

Column Newcrom R1, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 30/70%
Buffer H3PO4- 0.2%
Flow Rate 1.0 ml/min
Detection UV, 220 nm
 

Description

Class of Compounds Drug, Acid, Hydrophobic, Ionizable, Immunosuppressant
Analyzing Compounds Mycophenolate mofetil, Mycophenolic Acid
 

Application Analytes:

Mycophenolate mofetil
Mycophenolic acid

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