Nizatidine

CAS Number 76963-41-2
Molecular Formula C12H21N5O2S2
Molecular Weight 331.450 g/mol
InChI Key SGXXNSQHWDMGGP-UHFFFAOYSA-N
LogP 0.235
Synonyms
  • Nizatidine
  • N1-{2-[({2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl}methyl)sulfanyl]ethyl}-N'1-methyl-2-nitroethene-1,1-diamine
  • 1,1-Ethenediamine, N-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N'-methyl-2-nitro-
  • 76963-41-2
  • 1,1-Ethenediamine, N-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N'-methyl-2-nitro-
  • 1,1-Ethenediamine, N'-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N-methyl-2-nitro-
  • Calmaxid
  • Cronizat
  • Distaxid
  • Gastrax
  • N-[2-[2-[(Dimethylamino)methyl]-1H-imidazole-1-yl]-5-nitrophenyl]methanone
  • Naxidine
  • Nizaxid
  • Zanizal
  • BRN 4846056
  • N-(2-(((2-((Dimethylamino)methyl)-4-thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine
  • 1,1-Ethenediamine, N-(2-(((2-((dimethylamino)methyl)-4-thiazoly)methyl)thio)ethyl)-N'-methyl-2-nitro-
  • N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamin
  • Ulcosol
  • Antizid
  • Galitidin
  • Panaxid
  • Splendil ER
  • Axid AR
  • Nizatidina
  • Nizatidinum
  • UNII-P41PML4GHR
  • N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamine

Applications:


HPLC Method for Analysis of Nizatidine
2

Nizatidine is a competitive and reversible histamine H2-receptor antagonist. It is used for the treatment of duodenal ulcers, acid-peptic disease and heartburn. In some rare instances, the drug can cause a clinically apparent acute injury of the liver. Primesep 200 which is a reverse phase column, contains embedded acidic ionizable groups and can retain Nizatidine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Analytes:

Nizatidine