N,N-Dimethyl-5-methoxytryptamine

CAS Number 1019-45-0
Molecular Formula C13H18N2O
Molecular Weight 218.29 g/mol
InChI Key ZSTKHSQDNIGFLM-UHFFFAOYSA-N
LogP 1.5
Synonyms
  • N,N-Dimethyl-5-methoxytryptamine
  • 5-Methoxy-N,N-dimethyltryptamine
  • 1019-45-0
  • Methoxybufotenin
  • O-Methylbufotenine
  • MeODMT
  • 5-MeO-DMT
  • Methylbufotenine
  • 5-Methoxydimethyltryptamine
  • Bufotenine, O-methyl-
  • 3-(2-Dimethylaminoethyl)-5-methoxyindole
  • 2-(5-Methoxy-1H-indol-3-yl)-N,N-dimethylethanamine
  • 1H-Indole-3-ethanamine, 5-methoxy-N,N-dimethyl-
  • CT 4334
  • Methoxydimethyltryptamines
  • 5-Methoxy-N,N-dimethyl-1H-indole-3-ethanamine
  • UNII-X0MKX3GWU9
  • NSC 88624
  • INDOLE, 3-(2-(N,N-DIMETHYLAMINO)ETHYL)-5-METHOXY-
  • 5-OMe-DMT

Applications:

HPLC Separation of Biogenic Amines on Primesep 100 Column
Tryptophan is an essential amino acid used in the synthesis of proteins. Tryptamine is structurally similar to tryptophan. Serotonin is a neurotransmitter derived from tryptophan. Dimethyltryptamine and 5-MeO-DMT are psychedelic substances derived from tryptamine. All the compounds have similar structures and can present difficulties to separation in reverse-phase HPLC. They can be separated using the Primesep 100 mixed-mode column in gradient analysis with acetonitrile (ACN) and water mobile phase with ammonium formate (AmFm) buffer, making the method MS-compatible. The amines can also be UV detected at 280nm.

Condition
Column Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 40-50%, 15 min
Buffer Gradient AmFm pH 3.0- 20-80 mM, 15 min
Flow Rate 1.0 ml/min
Detection UV 280 nm,  MS-compatible mobile phase
 

Description
Class of Compounds Drug, Hydrophilic, Supplements, Monoamine,  Neurotransmitter
Analyzing Compounds Serotonin, Tryptophan, N,N-dimethyltryptophan, N,N-Dimethyl-5-methoxytryptamine, Tryptamine, N,N-dimethyltryptamine
 
Application Analytes:

N,N-Dimethyl-5-methoxytryptamine
N,N-Dimethyltryptamine
N,N-dimethyltryptophan
Serotonin
Tryptamine
Tryptophan