Pralidoxime Chloride

Pralidoxime chloride

Pralidoxime chloride has its most critical effect in relieving paralysis of the
muscles of respiration.

CAS Number51-15-0
Molecular FormulaC7H9ClN2O
Molecular Weight172.61
InChI KeyHIGSLXSBYYMVKI-UHFFFAOYSA-N
Synonyms
  • 2-PAM chloride
  • 51-15-0
  • ComboPen
  • Protopam chloride
  • Pralidoxine chloride
  • Protopam
  • Pralidoxime (chloride)
  • Pyridine-2-aldoxime methochloride
  • Pyridinium aldoxime methochloride
  • 2-Pyridine aldoxime methyl chloride
  • N-Methylpyridine-2-aldoxime chloride
  • 2-Pyridine-aldoxime chloride
  • Pralidoxime chloride [USAN]
  • N-Methylpyridinium chloride 2-aldoxime
  • N-Methylpyridinium-2-aldoxime chloride
  • UNII-38X7XS076H
  • 1-Methyl-2-pyridinium aldoxime chloride
  • 1-Methyl-2-aldoximinopyridinium chloride
  • 2-Formyl-1-methylpyridinium chloride oxime
  • 2-Formyl-N-methylpyridinium oxime chloride
  • 2-PAM
  • EINECS 200-080-9
  • 2-Hydroxyiminomethyl-1-methylpyridinium chloride
  • N-Metylpyridinium-2-aldoxime chloride
  • NSC 164614
  • 1-Methyl-2-formylpyridinium chloride oxime
  • MLS000028727
  • CHEBI:8355
  • 38X7XS076H
  • 2-(Hydroxyiminomethyl)-1-methylpyridinium chloride
  • NSC-164614
  • Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, chloride
  • SMR000059189
  • DSSTox_CID_3495
  • Pralidoxime chloride (USP)
  • Pralidoxime chloride [USP]
  • DSSTox_RID_77053
  • DSSTox_GSID_23495
  • Pyridinium, 2-formyl-1-methyl-, chloride, oxime
  • 2-Pyridinealdoxime methochloride
  • Q-201609
  • 2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium chloride
  • NSC164614
  • Pralidoximchlorid
  • Pralidoximechloride
  • Pralidoxime chloride [USAN:USP]
  • Protopam (TN)
  • Pralidoxime (INN)
  • Pam 2Cl
  • 2-PAM (chloride)
  • AC1NSDWQ
  • Opera_ID_228
  • AC1Q1RUT
  • CAS-51-15-0
  • 2-PAM-Cl
  • NCGC00016226-01
  • C7H9N2O.HCl
  • Pralidoxime chloride [MI]
  • Pyridinium, chloride, oxime
  • SCHEMBL61419
  • 2-[(1E)-(hydroxyimino)methyl]-1-methylpyridin-1-ium chloride
  • MLS001076535
  • MLS002222315
  • MLS003876809
  • Pralidoxime chloride [VANDF]
  • 2-[(hydroxyimino)methyl]-1-methylpyridinium chloride
  • Pralidoxime chloride [MART.]
  • Pralidoxime chloride [USP-RS]
  • Pralidoxime chloride [WHO-DD]
  • SCHEMBL1650343
  • DTXSID1023495
  • MolPort-004-440-359
  • HMS1570N08
  • HMS2097N08
  • HMS3259I04
  • HMS3714N08
  • Pharmakon1600-01505449
  • WLN: T6KJ A1 B1UNQ &G
  • 14018-50-9
  • Atnaa component pralidoxime chloride
  • HY-B1200
  • Pralidoxime chloride [GREEN BOOK]
  • Tox21_110316
  • MFCD00011981
  • NSC759147
  • Pralidoxime chloride [ORANGE BOOK]
  • s4575
  • Duodote component pralidoxime chloride
  • AKOS001094374
  • Tox21_110316_1
  • CCG-220943
  • CS-4828
  • FCH2256196
  • MCULE-2476744627
  • NSC-759147
  • Pralidoxime chloride component of atnaa
  • RTR-018235
  • NCGC00178286-05
  • Pralidoxime chloride component of duodote
  • AK324432
  • AN-41590
  • AS-13850
  • BBV-34551052
  • CPD000059189
  • SAM002554924
  • 2-Formyl-L-methylpyridinium chloride oxime
  • LS-132536
  • TR-018235
  • ST50825032
  • EN300-50184
  • D00469
  • J10435
  • M-2760
  • A828463
  • (1-methyl-2-pyridinylidene)methyl-oxoammonium chloride
  • (hydroxyimino)(1-methyl(2-pyridyl))methane, chloride
  • 2-[(hydroxyimino)methyl]-1-methylpyridin-1-ium chloride
  • [(E)-(1-methyl-2-pyridylidene)methyl]-oxo-ammonium chloride
  • [(E)-(1-methylpyridin-2-ylidene)methyl]-oxoazanium chloride
  • (1-methylpyridin-2-ylidene)methyl-oxidanylidene-azanium chloride
  • Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, chloride (E)-
  • Pyridinium, 2-[(hydroxyimino)methyl]-1-methyl-, chloride (1:1)
  • Pralidoxime chloride, United States Pharmacopeia (USP) Reference Standard

Applications:

HPLC Separation of Mixture of Atropine, Atrolactic Acid and Pralidoxime Chloride

April 15, 2019

HPLC Method for Atropine, Atrolactic Acid, Pralidoxime Chloride on Primesep 200 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Atropine, Atrolactic Acid, Pralidoxime Chloride.

Atropine is a tropane alkaloid with the chemical formula C17H23NO3. It is an anticholinergic medication that is used to treat nerve agent, pesticide poisoning, slow heartrate, and is also used to decrease saliva production. Typically, it is administered through injection.

Atrolactic Acid is a 2-hydroxy monocarboxylic acid with the chemical formula C9H10O3. It can cause irritation to eyes, skin, and the respiratory system.

Pralidoxime Chloride, also known as 2-PAM, is a cholinesterase reactivator with the chemical formula C7H9N2O+. It is used as an antidote for poisoning by organophosphate pesticides and nerve agents.

Atropine, Atrolactic Acid, Pralidoxime Chloride can be retained and analyzed using the Primesep 200 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a [buffer] buffer. Detection is performed using UV.

Condition

Column Primesep 200, 4.6 x 150 mm, 3 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 20/80%
Buffer Gradient H3PO4 – 0.1-0.3%, 10 min
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description

Class of Compounds
Drug, Acid, Base, Hydrophilic, Hydrophobic, Ionizable, Vitamin, Supplements
Analyzing Compounds Atropine, Atrolactic Acid, Pralidoxime Chloride

 

Application Column

Primesep 200

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Atrolactic Acid
Atropine
Pralidoxime Chloride

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Determination of Pralidoxime Chloride on Primesep 200 Column

April 15, 2019

HPLC Method for Pralidoxime Chloride on Primesep 200 by SIELC Technologies

HPLC Determination of Pralidoxime Chloride

High Performance Liquid Chromatography (HPLC) Method for Analysis of Pralidoxime Chloride.

Pralidoxime Chloride, also known as 2-PAM, is a cholinesterase reactivator with the chemical formula C7H9N2O+. It is used as an antidote for poisoning by organophosphate pesticides and nerve agents.

Pralidoxime Chloride can be retained and analyzed using the Primesep 200 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a [buffer] buffer. Detection is performed using UV.

Condition

Column Primesep 200, 4.6 x 150 mm, 3 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 20/80%
Buffer H3PO4 – 0.1%
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description

Class of Compounds
Drug, Basic, Hydrophobic, Ionizable
Analyzing Compounds Pralidoxime Chloride

 

Application Column

Primesep 200

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Pralidoxime Chloride

Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.