Newcrom R1

Newcrom R1 stationary phase is generally stable at basic pH values.

Recommended pH is from 1.0 to 10.0. As an example, we performed a test where the column was operated at pH of 10.6 by injecting a model mixture of a neutral, basic, and acidic compounds.  This experiment took over 15 hours and after almost 200 injections no significant loss or changes in retention were observed.

However, despite the fact that this stationary phase is stable at high pH, it is recommended for column storage to use acidic mobile phase. A mobile phase composition with 0.1% phosphoric or formic acid in a 50/50 mixture of MeCN/H2O should be an ideal long and short term storage solution.

Newcrom R1 columns are available in all standard dimensions
Column IDs: 22 mm, 10 mm, 4.6 mm, 3.2 mm, 2.1 mm
Column Lengths: 250, 150, 100, 50, 25, 10 mm
Particles: 5 µm and 3 µm
Pores: 100 A

This column is available in two hardware versions traditional two ended and new SIELC hardware with only one end.

Newcrom

Newcrom R1 stationary phase is generally stable at basic pH values.
Recommended pH is from 1.0 to 10.0. Newcrom C18 pH rangeAs an example, we perform a test where the column was operated at pH 10.6 injecting a model mixture of a neutral, basic, and acidic compounds. This experiment took over 15 hrs and after almost 200 injections no significant lost or changes of retention were observed.
However despite the fact that this stationary phase is stable at high pH it is recommended for column storage to use acidic mobile phase. A mobile phase composition with 0.1% phosphoric or formic acid in 50/50 mixture of MeCN/H2O should be an ideal long and short term storage solution.

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Newcrom R1 Application Examples

HPLC Determination of 6-methyl-5-hepten-2-one

HPLC Separation of Mixture of Mycophenolate mofetil and Mycophenolic Acid
HPLC Method for Analysis of Fluticasone Propionate in Nasal Spray
HPLC Method for Analysis of Pantoprazole Sodium in Tablets
HPLC Method for Analysis of Nitroglycerin
HPLC Method for Analysis of Quetiapine in Tablets
HPLC Method for Analysis of Doxazosin Mesylate in Tablets
HPLC Method for Analysis of Ethyl red
HPLC Method for Analysis of D-alpha-Tocopheryl acetate
HPLC Method For Analysis Of Alprazolam
HPLC Method For Analysis Of Minocycline hydrochloride
HPLC Method for Analysis of Dansyl Amino Acids
HPLC Separation of Acetaminophen, Caffeine and Pyrilamine maleate
HPLC Method for Analysis of Dyes
HPLC Method for Analysis of Metronidazole
HPLC Method for Analysis of Warfarin
HPLC Method for Analysis of Verapamil