Pyrilamine maleate

Pyrilamine maleate structural formula

CAS Number 59-33-6
Molecular Formula C21H27N3O5
Molecular Weight 401.464 g/mol
InChI Key JXYWFNAQESKDNC-BTJKTKAUSA-N
LogP 2.82
Synonyms
  • Pyrilamine maleate
  • (2Z)-But-2-enedioic acid--N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine (1/1)
  • 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate (1:1)
  • 59-33-6
  • 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-,
  • 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-,
  • 2-[(2-Dimethylaminoethyl)(p-methoxybenzyl)amino]-pyridine maleate
  • 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine Bimaleate
  • Anisopyradamine
  • Antamine
  • Anthisan maleate
  • Antihist
  • Antisan
  • Diaminide maleate
  • Enrumay
  • Histalet Forte
  • Histalon
  • Histapyran
  • Histatex
  • Histavet P
  • maleate de mepyramine
  • maleato de mepiramina
  • MALEINSAEURE-(2-(N-(2-DIMETHYLAMINO-AETHYL)-N-(P-METHOXY-BENZYL)-AMINO)-PYRIDIN) - SALZ
  • Mepyramine hydrogen maleinate
  • mepyramine maleate
  • Mepyraminmaleat
  • Minihist
  • Neoantergan maleate
  • Neo-Antergan maleate
  • N-p-Methoxybenzyl-N',N'-dimethyl-N-?-pyridylethylenediamine maleate
  • NSC 3604
  • Paramal
  • Paraminyl
  • Paraminyl maleate
  • Prefrin A
  • Pymafed
  • Pyra Maleate
  • Pyramal
  • Pyranilamine maleate
  • Pyraninyl
  • Pyranisamine maleate
  • Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-, maleate (1:1)
  • Renstamin
  • Stamine
  • Stangen
  • Stangen maleate
  • Statomin maleate
  • Thylogen
  • Thylogen maleate
  • 2786 R.P. maleate
  • N-Dimethylaminoethyl-N-p-methoxy-alpha-aminopyridine maleate
  • N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyridyl)ethylenediamine maleate
  • Dorantamin maleate
  • EINECS 200-422-7
  • Histine
  • Histosol
  • Kriptin maleate
  • N-p-Methoxybenzyl-N',N'-dimethyl-N-alpha-pyridylethylenediamine maleate
  • Pyramal maleate
  • Pyra-Maleate
  • UNII-R35D29L3ZA
  • 5572-06-5

Applications:


Separation of Pyrilamine maleate on Newcrom R1 HPLC column

Pyrilamine maleate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Separation of Pyrilamine maleate on Newcrom C18 HPLC column
Newcrom R1

This column is available in new type of hardware with only one connection end. Learn more about performance and advantage of this new hardware.



Application Analytes:

Pyrilamine maleate

HPLC Separation of Acetaminophen, Caffeine and Pyrilamine maleate
Acetaminophen is a p-aminophenol derivative with analgesic and antipyretic activities. It has weak anti-inflammatory properties, may cause liver, blood cell, and kidney damage. It is a nonprescription medication for mild-to-moderate pain and fever. Caffeine is a Central Nervous System (CNS) stimulant. It is an unregulated and legal drug in most parts of the world. It can be found in the seeds and leaves in a number of plants native in Africa, East Asia and South America. Pyrilamine maleate is a histamine H1 antagonist with hypnotic properties. It has multiple uses such as an anesthetic and is used against allergies. Newcrom R1, a column that takes advantage of the newest technologies, does not contain embedded acidic nor basic ionizable groups and can retain Acetaminophen, Caffeine and Pyrilamine maleate. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Analytes:

Acetaminophen (Paracetamol)
Caffeine
Maleate
Pyrilamine
Pyrilamine maleate