| CAS Number | 26652-09-5 |
|---|---|
| Molecular Formula | C17H21NO3 |
| Molecular Weight | 287.360 |
| InChI Key | IOVGROKTTNBUGK-SJCJKPOMSA-N |
| LogP | 1.63 |
| Synonyms |
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Applications:
UV-Vis Spectrum of Ritodrine
July 2, 2024
Access the UV-Vis Spectrum SIELC Library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
HPLC Determination of Ritodrine on Primesep 100
August 7, 2019
HPLC Method for Ritodrine on Primesep 100 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Ritodrine
Ritodrine (also Yutopar), is a drug used in relaxation of smooth muscle and to stop premature labor. It has been pulled from the US market due to its side effects. Ritodrine can be retained on a Primesep 100 column with great peak shape using isocratic method of 30/70 Acetonitrile (ACN) and water with 0.3% sulfuric acid as buffer. UV Detection 276nm.
Condition
Column Primesep 100, 4.6×150 mm, 5 µm, 100A Mobile Phase MeCN/H2O – 30/70% Buffer H2SO4 – 0.3 % Flow Rate 1.0 ml/min Detection UV, 276 nm
Description
Class of Compounds
Drug, Basic, Hydrophobic, Ionizable, Amine Analyzing Compounds Ritodrine
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Separation of Ritodrine on Newcrom R1 HPLC column
May 16, 2018
Ritodrine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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