Sulfaguanidine

CAS Number 57-67-0
Molecular Formula C7H10N4O2S
Molecular Weight 214.25 g/mol
InChI Key BRBKOPJOKNSWSG-UHFFFAOYSA-N
LogP -0.7
Synonyms
  • sulfaguanidine
  • 57-67-0
  • Sulfaguanidin
  • Sulphaguanidine
  • Sulfaguine
  • Guanicil
  • Sulfanilguanidine
  • Sulfoguanidine
  • Sulfaguanil
  • Sulfanilylguanidine
  • Sulfoguanil
  • Sulfoguanyl
  • Abiguanil
  • Guanidan
  • Sulfentidine
  • Aterian
  • Guamide
  • Orgaguanidon
  • Sulfaguanidinum
  • Sulfoguenil
  • Sulfoquanidine
  • Ganidan
  • N1-Amidinosulfanilamide
  • Resulfon
  • Suganyl
  • Diacta
  • Ruocid
  • Sulgin
  • N-Guanylsulfanilamide
  • S-Guanidine
  • 1-Sulfanilylguanidine
  • Sulfaguanidina
  • Shigatox
  • Guanidine, sulfanilyl-
  • p-Aminobenzenesulfonylguanidine
  • p-Aminobenzenesulfoguanidide
  • Sulginum
  • RP 2275
  • 2-(4-aminophenyl)sulfonylguanidine
  • Benzenesulfonamide, 4-amino-N-(aminoiminomethyl)-
  • Sulfanilamide, n(sup1)-amidino-
  • 4-Amino-N-(aminoiminomethyl)benzenesulfonamide
  • ((p-Aminophenyl)sulfonyl)guanidine
  • ((4-Aminophenyl)sulfonyl)guanidine
  • 1-((p-Aminophenyl)sulfonyl)guanidine
  • Solfaguanidina [DCIT]
  • Sulfaguamidine
  • 4-Amino-N-(diaminomethylene)benzenesulfonamide
  • A-307
  • Sulfanilamide, N1-amidino-
  • N-p-Aminobenzenesulphonylguanidine monohydrate
  • Sulfaguanidinum [INN-Latin]
  • N(sup 1)-Guanylsulfanilamide
  • Sulfaguanidina [INN-Spanish]
  • 4-Aminobenzenesulfonylguanidine
  • UNII-15XQ8043FN
  • N(sup 1)-Amidinosulfanilamide
  • 4-amino-N-[amino(imino)methyl]benzenesulfonamide
  • C7H10N4O2S
  • 4-amino-N-carbamimidoylbenzenesulfonamide
  • Emerin (pharmaceutical) (VAN)
  • Sulfaguanidine [INN]
  • Emerin (pharmaceutical)
  • EINECS 200-345-9
  • NSC 14041
  • Benzenesulfonamide, 4-amino-N-(diaminomethylene)-
  • N(sup 1)-(Diaminomethylene)sulfanilamide
  • AI3-01048
  • CHEMBL338802
  • BRBKOPJOKNSWSG-UHFFFAOYSA-N
  • 15XQ8043FN
  • 1-(4-aminophenyl)sulfonylguanidine
  • Sulfanilamide, N(sup 1)-amidino-
  • 2-(4-aminobenzenesulfonyl)guanidine
  • N-(4-aminobenzenesulfonyl)guanidine
  • Sulfaguanidine (INN)
  • Sulfaguanidine, 98%
  • CAS-57-67-0
  • NCGC00016252-01
  • Solfaguanidina
  • amino[(4-aminophenyl)sulfonyl]carboxamidine
  • 4-Amino-N-carbamimidoylbenzene-1-sulfonamide
  • 4-Amino-N-diaminomethylene-benzenesulfonamide
  • DSSTox_CID_3609
  • 4-amino-N-(diaminomethylidene)benzenesulfonamide
  • DSSTox_RID_77107
  • DSSTox_GSID_23609
  • [(p-Aminophenyl)sulfonyl]guanidine
  • [(4-Aminophenyl)sulfonyl]guanidine
  • 1-[(p-Aminophenyl)sulfonyl]guanidin

Applications:


HPLC Separation of Antibiotics
HPLC.cloud View on hplc.cloud Antibiotics are widely used for treatment and prevention of bacterial infections.  Various antibiotics, particularly those with a sulfanilamide structure, were separated in HPLC using mixed-mode columns with varying strengths of ion-pairing groups.  Primesep 200 has weak acidic ion-exchange pairing groups while Newcrom A has strong acidic ion-exchange groups.  In addition, methanol can be used in the mobile phase on Newcrom A column.  The antibiotics were resolved on both columns with a gradient mobile phase consisting of acetonitrile (ACN) or methanol (MeOH), water and sulfuric acid (H2SO4) buffer.  UV detection at 275nm.

Condition 1

Column Primesep 200, 4.6x100 mm, 5 µm, 100A
Mobile Phase MeCN Gradient
Buffer H2SO4 - 0.5%
Flow Rate 1.0 ml/min
Detection UV 275 nm

Condition 2

Column Newcrom A, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeOH Gradient
Buffer H2SO4 Gradient
Flow Rate  0.5 ml/min
Detection UV 275 nm
 

Description

Class of Compounds Drugs, Antibiotics
Analyzing Compounds Sulfanilamide, Sulfadiazine, Sulfaguanidine, Dapsone, Sulfaquinoxaline


Application Analytes:

Dapsone
Sulfadiazine
Sulfaguanidine
Sulfanilamide
Sulphaquinoxaline