Tamsulosin

CAS Number 106133-20-4
Molecular Formula C20H28N2O5S
Molecular Weight 408.511 g/mol
InChI Key DRHKJLXJIQTDTD-OAHLLOKOSA-N
LogP 2.06
Synonyms
  • Tamsulosin
  • 5-[(2R)-2-{[2-(2-Ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonamide
  • Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-
  • 106133-20-4
  • Benzenesulfonamide, 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-
  • (R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
  • Tamsulosina
  • Tamsulosine
  • Tamsulosinum
  • Flowmax
  • UNII-G3P28OML5I
  • 5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide

Applications:


HPLC Method for Analysis of Tamsulosin
Chr_1044

Tamsulosin is chemically 5-{(2R)-2[{2-(2-ethoxyphenoxy)ethyl} amino]propyl}-2-methoxybenzene sulfonamide and a selective α1 adrenoceptor blocking agent. It is used to treat BPH (benign prostatic hyperplasia). The treatment is associated with a low rate of serum aminotransferase elevations. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Tamsulosin. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Condition

Column Primesep 200, 3.2x100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 5-50%
Buffer Gradient H3PO4 - 0.05-0.3%, 5 min, 4 min hold
Flow Rate 0.5 ml/min
Detection UV, 270 nm
   

Description

Class of Compounds Drug,  Acid, Hydrophilic, Ionizable,
Analyzing Compounds Tamsulosin


Application Analytes:

Tamsulosin