USP Methods Analysis of Procainamide Legacy L1 Column

  Application Columns: Legacy L1 C18 HPLC column Application compounds: Procainamide and 4-aminobenzoic acid Mobile phase: WAter/MeOH/MeCN (70/70/90) with 7 mM sodium lauryl sulfate and 11mM phosphoric acid Detection technique: UV Reference: USP35: NF30


Column Legacy L1, 4.6x150 mm, 5 µm, 100A
Mobile Phase Water/MeOH/TEA (140/60/1)   adjusted to pH 7.5 with H3PO4
Buffer TEAPh
Flow Rate 1.5 ml/min
Detection UV, 230 nm


Class of Compounds Drug, Nonsteroidal anti-inflammatory drug, Hydrophobic, Ionizable
Analyzing Compounds Ibuprofen, benzophenone

Application Analytes:

4-Aminobenzoic Acid
Procainamide Hydrochloride